Cardiometabolic late complications in survivors: of acute lymphoblastic leukemia: prevalence and biomarkers
Valérie Marcil, M.Sc., Ph.D.
Dr. Valerie Marcil is an Assistant professor researcher in the Department of nutrition, Université de Montréal since 2014 and a researcher at Sainte-Justine Hospital Research Center. She is a registered nutritionist and has completed her Master’s degree in 2002 and her PhD in nutrition with Honors at the University of Montreal in 2008. Subsequently, she has completed her post-doctoral training in the Departments of Medicine and Pediatrics at McGill University to study new susceptibility genes in inflammatory bowel disease, lipid metabolism and transport, cardiometabolic diseases, as well as nutritional status in patients with inflammatory bowel disease. Following this, she completed a second post-doctorate at Sainte-Justine Hospital Research Center as part of the PETALE team (Prevention of long-term treatment effects in childhood acute lymphoblastic leukemia survivors) to study cardiometabolic complications in survivors of acute lymphoblastic leukemia. Her training research record includes 24 publications and funds through 14 different grants and scholarships
As a young investigator, Dr Marcil’s research interests program aims at determining the causes of cardiometabolic complications in survivors of pediatric cancers, mainly leukemia. Thanks to the Cole Foundation transition grant, Dr Marcil’s laboratory will investigate the impact of nutrition, oxidative stress, inflammation, microbiota, and epigenetic regulations in the development of these late effects. Her long-term goal is to prevent long-term effects of pediatric cancer treatment using nutritional strategies. Understanding the underlying mechanisms of cardiometabolic late effects will allow the identification of novel targets for preventive and curative intervention and will contribute to achieve the full potential of nutrition therapy for preventive and curative intervention in this high-risk population.